Search on: PROTEIN PHOSPHATASE 1 
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Descriptor English:   Protein Phosphatase 1 
Descriptor Spanish:   Proteína Fosfatasa 1 
Descriptor Portuguese:   Proteína Fosfatase 1 
Tree Number:   D08.811.277.352.650.625.687
Definition English:   A eukayrotic protein serine-threonine phosphatase subtype that dephosphorylates a wide variety of cellular proteins. The enzyme is comprised of a catalytic subunit and regulatory subunit. Several isoforms of the protein phosphatase catalytic subunit exist due to the presence of multiple genes and the alternative splicing of their mRNAs. A large number of proteins have been shown to act as regulatory subunits for this enzyme. Many of the regulatory subunits have additional cellular functions. 
History Note English:   2008(1983); for PROTEIN PHOSPHATASE-1 use PHOSPHOPROTEIN PHOSPHATASES 1984-2007 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52693 
Unique Identifier:   D054645 

Occurrence in VHL:
 

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